Skip to main content

Why estrogen is important for men?
While testosterone replacement therapy (TRT) is primarily focused on increasing testosterone levels in men with low testosterone, estrogen still plays an important role in the overall balance of hormones. For men on TRT, estrogen can have both beneficial and potentially problematic effects, depending on the level it reaches and how it is managed. Here is how estrogen can be beneficial, as well as why it needs to be carefully monitored:

1. Bone Health
Estrogen is important for maintaining bone density in both men and women. Even though men have lower levels of estrogen than women, it still plays a significant role in bone health. During TRT, if testosterone levels rise too much without sufficient estrogen, it can result in lower bone density and increased risk of osteoporosis. A balanced level of estrogen can help protect bone strength and reduce the risk of fractures.

2. Cardiovascular Health
Estrogen can help support vascular health by maintaining the flexibility of blood vessels and supporting healthy cholesterol levels. Low estrogen can contribute to increased cardiovascular risk in men. A small amount of estrogen is typically produced in men from the aromatization of testosterone. Having a sufficient level of estrogen helps to balance lipid profiles (cholesterol), potentially reducing the risk of heart disease.

3. Mood and Mental Well-being
Estrogen, like testosterone, affects neurotransmitters in the brain, such as serotonin and dopamine, which influence mood and emotional health. Men undergoing TRT may benefit from estrogen’s influence on mood stabilization and cognitive function. Estrogen helps promote a
sense of well-being, reduces feelings of irritability, and can counteract mood swings that may arise with shifts in testosterone levels.

4. Sexual Function
Estrogen contributes to maintaining sexual health in men. While testosterone is the primary hormone responsible for libido and erectile function, a small amount of estrogen is necessary to maintain healthy erectile function. Too little estrogen in men can contribute to erectile
dysfunction or other sexual issues, which is why a careful balance between testosterone and estrogen is important during TRT.

5. Preventing Gynecomastia (Breast Tissue Growth)
One of the potential side effects of TRT is the conversion of excess testosterone into estrogen via a process called aromatization. If testosterone levels rise too quickly or too high, the increase in estrogen can cause gynecomastia, or the development of breast tissue in men. In some cases, physicians may monitor estrogen levels and use medications like aromatase inhibitors to prevent excessive estrogen conversion. On the other hand, some estrogen is necessary for overall health, so finding the right balance is key.

6. Skin Health

Estrogen has benefits for skin elasticity and hydration, which can improve the overall appearance of the skin. In men undergoing TRT, balanced estrogen levels can contribute to healthier, more youthful skin. This can help prevent issues such as excessive dryness or
thinning that can occur with hormone imbalances.

7. Fat Distribution
Estrogen helps with the distribution of body fat. In men, this means it can help prevent the accumulation of fat around the abdomen, which is often seen when testosterone levels are out of balance. Having a healthy level of estrogen can contribute to a more appropriate fat
distribution, reducing the risk of abdominal obesity and associated health issues, such as metabolic syndrome.

Summary                                                                                                                                                                                                                                    While TRT is intended to increase testosterone levels, estrogen plays a supporting but crucial role in overall health. A healthy balance of estrogen helps improve bone density, cardiovascular health, mood, and sexual function. The key is to ensure estrogen levels don’t get
too high or too low during treatment, so regular monitoring is essential to achieve optimal hormone balance.

One of the easiest ways to help balance estrogen levels in men on TRT is by using a DIM supplement. DIM (Diindolylmethane) is a compound that is naturally formed in the body when we digest cruciferous vegetables, like broccoli, cabbage, kale, and Brussels sprouts. For men, it is sometimes used to support healthy testosterone levels by promoting estrogen metabolism.

For a more in-depth review of the effects of estrogen in men please read this comprehensive paper.